GTEx V10 Data Release on AnVIL
We are excited to announce the availability of GTEx V10 data on the AnVIL platform!
The GTEx (Genotype-Tissue Expression) consortium has just released version 10 of its comprehensive dataset, advancing research on human gene expression and its regulation across tissues. This release offers a wealth of new resources for the research community:
What's New in GTEx V10?
- Expanded RNA-seq Data: V10 includes 12% more RNA-seq samples than the previous V8 release.
- Enhanced eQTL Analyses: Researchers can now access 23% more samples used in eQTL analyses.
- Small RNA-seq Data: V10 introduces smallRNA-seq data from 16,760 tissue samples, including gene expression counts and cis-QTLs.
- Deep Somatic Whole Genome Sequencing (WGS): High-coverage (~195X) somatic WGS data from 199 samples, spanning 5-7 tissue types from 55 donors, are now available.
- Genotyping of All Adult Donors: While this data was initially included in V9, it complements the wealth of V10 data for broader integrative analyses.
Accessing GTEx V10 Data on AnVIL
Researchers can now access GTEx V10 controlled access data through the AnVIL platform, which also provides cloud-based infrastructure for scalable genomics analysis. GTEx V10 open access data is also available for download via the GTEx Open Access Download page.
For access to controlled data, including individual-level genotypes and phenotypes:
- Request access through dbGaP: The GTEx dataset can be found on dbGaP under accession phs000424.v10.p1.
- Leverage DUOS for streamlined access: Researchers can also utilize the Data Use Oversight System (DUOS) to request and manage access to GTEx data, ensuring compliance with data use agreements efficiently. Step-by-step instructions to access GTEx data for analysis in Terra can be found here: https://support.terra.bio/hc/en-us/articles/30873545719451-How-to-access-GTEx-data-in-Terra
We invite researchers to explore GTEx V10 on the AnVIL platform and take advantage of its cutting-edge resources to drive new discoveries in genomics.
For more details on accessing and analyzing GTEx V10 data, visit AnVIL Project or reach out via help.anvilproject.org.