Description

First organized in 2019, the NIH Cloud Platform Interoperability (NCPI) Effort’s goal is to establish and implement guidelines and technical standards to empower end-user analyses across the four participating platforms and facilitate the realization of a trans-NIH, federated data ecosystem. NCPI is a collaborative project between five NIH Institutes and Centers (NCI, NHGRI, NHLBI, NIH Common Fund, and NCBI) as well as external partners comprising six Working Groups: Coordination, Community Governance, FHIR, Outreach and Training, NIH Systems Interoperation, and Search.

This workshop was open to the public and held on 22-23 June, 2022 from 11:00 AM - 4:00 PM EDT. We hope this meeting engaged presenters and participants alike, providing guidance and vision to drive interoperability of NIH Cloud Platforms.

The meeting comprised five main sessions of speakers, outlined below. Following the talks on each day, moderated breakout sessions were opened to allow for community discussion and input.

• FAIR Data, Computing, Cataloging Resources Across the NIH and Global Communities: The vision shared in this session will provide foundation and direction to chart the collaborative future of NCPI.
• Panel Discussion with Commercial Cloud Vendors.
• Interoperability Driven Science: Cloud platform interoperability enables scientific discovery. Here we will learn of the latest advances in NCPI demonstration projects.
• NCPI Working Group Updates
• Technical Aspects of Interoperability: Technologies that enable interoperability are important to develop with stakeholders involved to promote the usability of the technical standards and products. In this session, we will hear about technologies enabling interoperability and their successful implementations in research.

Please reach out with questions or comments by emailing Stephen Mosher at smosher3@jhu.edu.

Recordings

Recordings of Day 1 and Day 2 of the workshop can be found below.

Day 1

Day 2

Agenda

Day 1: Wednesday, June 22, 2022

11:00AM - 11:10AM	Welcome and goals of meeting Anthony Phillipakis (Broad Institute) and Michael Schatz (Johns Hopkins University)

FAIR Data, Computing, Cataloging Resources Across the NIH and Global Communities

The vision shared in this session will provide foundation and direction to chart the collaborative future of NCPI.

11:10AM - 11:30AM	The NIH Strategic Vision for Data Science, Successes and Opportunities for the Next 5 Years	Laura Biven (ODSS)
11:30AM - 11:50AM	ODSS All-Hands Meeting Report Out: Data and Compute Infrastructure	Tanja Davidsen (NCI)
11:50AM - 12:05PM	Interoperability in Data Mesh	Samia Rahman (Seagen)
12:05PM - 12:20PM	Integrating Data and Knowledge Across Multiple Species: The Importance of Biological Concept Harmonization	Carol Bult (The Jackson Laboratory)
12:20PM - 12:35PM	Playing telephone with data access: success with GA4GH DRS	Titus Brown (UC Davis)
12:35PM - 1:05PM	Break
1:05PM - 1:50PM	Panel Discussion with Commercial Cloud Vendors	Patrick Combes - Amazon Web Services Jer-Ming Chia - Microsoft Azure Adrish Sannyasi - Google Cloud Platform
1:50PM - 2:00PM	Break
2:00PM - 4:00PM	Parallel Breakout Sessions	20 min - Data Mesh - Allison Heath, Brian O'Connor 20 min - Reproducibility - Valentina Di Francesco, Mike Feolo 20 min - Resource and service readiness for AI/ML - Chris Wellington, Stan Ahalt 20 min - Engaging partnerships (i.e., GA4GH, Elixir, DOD, UKBiobank, NSF Cloudbank) - Kathy Reinold, Adam Resnick 5 min - Prep report back 25 min - Report back - Michael Schatz, Rachel Liao
4:00PM	Conclusion of Workshop Day 1

Day 2: Thursday, June 23, 2022

11:00AM - 11:05AM	Welcome and start of Day 2 Stephen Mosher (Johns Hopkins University)

Interoperability Driven Science

Cloud platform interoperability enables scientific discovery. Here we will learn of the latest advances in NCPI demonstration projects.

11:05AM - 11:20AM	The ELIXIR Cloud for European Life Sciences	Jonathan Tedds (ELIXIR)
11:20AM - 11:35AM	Sex chromosome complement aware alignments	Melissa Wilson (ASU)
11:35AM - 11:50AM	Genome-wide Sequencing Analysis to Identify the Genes Responsible for Enchondromatoses and Related Malignant Tumors	Nara Sobreira (JHU)
11:50AM - 1:05PM	Working Group Updates	15 min - Community/Governance WG - Bob Grossman (University of Chicago), Stanley Ahalt (University of North Carolina at Chapel Hill) 15 min - Systems Interoperation WG - Jack DiGiovanna (SevenBridges) 15 min - FHIR WG - Robert Carroll (Vanderbilt University Medical Center) 15 min - NCPI Outreach WG - Stephen Mosher (Johns Hopkins University) 15 min - Search WG - Dave Rogers (Clever Canary), Kathy Reinold (Broad Institute)
1:05PM - 1:35PM	Break

Technical Aspects of Interoperability

Technologies that enable interoperability are important to develop with stakeholders involved to promote the usability of the technical standards and products. In this session, we will hear about technologies enabling interoperability and their successful implementations in research.

1:35PM - 1:50PM	The Texas Advanced Computing Center (TACC) as an Interoperable Cloud Resource for Biomedical Research	Dan Stanzione (TACC)
1:50PM - 2:05PM	FHIR for Genomics: The Path Forward	Mullai Murugan (Baylor College of Medicine)
2:05PM - 2:20PM	Supporting Genomic Data Sharing through the Global Alliance for Genomics and Health	Heidi Rehm (Broad Institute)
2:20PM - 2:35PM	Interoperability Opportunities & Challenges with the Cloud and STRIDES	Nick Weber (NIH STRIDES)
2:35PM - 3:10PM	Concurrent Breakouts	Topic 1: Bringing researchers to cloud computing - Tiffany Miller Topic 2: Reproducibility and Interoperability of batch and ad hoc analyses - Jack DiGiovanna Topic 3: What technologies and data types are missing across platforms? - Ken Wiley Topic 4: Diversifying genomic data science - Asiyah Lin Topic 5: Flagship use cases for interoperability - Michael Schatz
3:10PM - 3:50PM	Report Back	5 min - Report prep 5 min - Report per group 10 min - Open discussion
3:50PM - 4:00PM	Summary, Future Directions, & Meeting close	Michael Schatz (Johns Hopkins University)
4:00PM	Meeting close

Contact

Stephen Mosher at smosher3@jhu.edu.