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Genomic Characterization of Metastatic Castration Resistant Prostate Cancer

phs001648.v2.p1dbGapdbGap FHIR

Description

Biopsies of castration resistant prostate cancer metastases were subjected to whole genome sequencing (WGS), along with RNA-sequencing (RNA-Seq). The overarching goal of the study is to illuminate molecular mechanisms of acquired resistance to therapeutic agents, and particularly androgen signaling inhibitors, in the treatment of metastatic castration resistant prostate cancer (mCRPC).

Summary

PlatformsCRDC
Consent CodesGRU
Focus / DiseasesProstatic Neoplasms, Castration-Resistant
Study DesignProspective Longitudinal Cohort
Data TypesBisulfite-Seq
Subjects101