NCPI
NIH Cloud PlatformInteroperability Effort
searchclose
YouYube

Study

arrow_backDatasets

NHLBI TOPMed: Severe Asthma Research Program (SARP)

phs001446.v1.p1dbGapdbGap FHIR

Description

The overall goal of the Severe Asthma Research Program (SARP) is to identify and characterize subjects with severe asthma to understand pathophysiologic mechanisms in severe asthma. Subjects with mild and moderate asthma were recruited for comparison but the program was enriched for subjects with severe asthma from multiple centers. Subjects were comprehensively phenotyped for asthma related traits including lung function, atopy, questionnaires on medical and family history, exhaled nitric oxide and health care utilization including exacerbations and symptoms. Asthma is a heterogenous disease. Cluster analysis in SARP has shown multiple subphenotypes and endotypes.

Summary

PlatformsBDC
Consent CodesGRU
Focus / DiseasesAsthma
Study DesignCase Set
Data TypesSNP/CNV Genotypes (NGS), WGS
Subjects1,882