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NHLBI TOPMed: Diabetes Heart Study (DHS) African American Coronary Artery Calcification (AA CAC)

phs001412.v2.p1dbGapdbGap FHIR

Description

The Diabetes Heart Study (DHS) is a family-based study enriched for type 2 diabetes (T2D). The cohort included 1443 European American and African American participants from 564 families with multiple cases of type 2 diabetes (Bowden et al., 2010. Review of Diabetic Studies 7:188-201. PMID: 21409311). The cohort was recruited between 1998 and 2006. Participants were extensively phenotyped for measures of subclinical CVD and other known CVD risk factors. Primary outcomes were quantified burden of vascular calcified plaque in the coronary artery, carotid artery, and abdominal aorta all determined from non-contrast computed tomography scans.

Summary

PlatformsBDC
Consent CodesNRUP, HMB-IRB-COL-NPU, DS-DHD-IRB-COL-NPU
Focus / DiseasesCardiovascular Diseases
Study DesignCross-Sectional
Data TypesSNP/CNV Genotypes (NGS), WGS
Subjects405