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NHLBI TOPMed: Genetic Epidemiology Network of Salt Sensitivity (GenSalt)

phs001217.v2.p1dbGapdbGap FHIR

Description

The GenSalt study aims to identify genes which interact with dietary sodium and potassium intake to influence blood pressure in Han Chinese participants from rural north China. Whole genome sequencing will be conducted among 1,860 participants of the Genetic Epidemiology Network of Salt Sensitivity (GenSalt) Study. We will work in collaboration with participating TOPMed studies to identify novel common, low-frequency and rare variants associated with an array of cardiometabolic phenotypes. In addition, we will explore the relation of low-frequency and rare variants with salt-sensitivity among GenSalt study participants.

Summary

PlatformsBDC
Consent CodesNRUP, DS-HCR-IRB
Focus / DiseasesArterial Pressure
Study DesignFamily/Twin/Trios
Data TypesSNP/CNV Genotypes (NGS), WGS
Subjects3,142