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Genes-Environments and Admixture in Latino Asthmatics (GALA II) Study

phs001180.v2.p1dbGapdbGap FHIR

Description

A case-control pharmacogenetic study of bronchodilator drug response among racially admixed Latino children with asthma. Each participant had two spirometry measurements using the KoKo PFT System. With the first spirometry test, participant was administered with 4 puffs of HFA Albuterol. The second albuterol measurement was based on age, for participants under 16 years of age, additional 2 puffs were administered and for those over 16 years of age, additional 4 puffs were administered. The overall goal is to identify genetic factors which are predictive of drug response in children with asthma. The principal tools include a questionnaire and biological specimen collection. Participants are 8-21 years old at time of recruitment. Children with asthma have physician-diagnosed asthma, symptoms and medications.

The GALAII Study is utilized in the following dbGaP substudies. To view genotypes, analysis, other molecular data, and derived variables collected in these substudies, please click on the following substudies below or in the "Substudies" box located on the right hand side of this top-level study page phs001180 GALAII Study. - phs001274phs001274 GALAII GWAS

Summary

PlatformsBDC
Consent CodesNRUP, DS-LD-IRB-COL
Focus / DiseasesLung Diseases
Study DesignCase-Control
Data TypesSNP Genotypes (Array)
Subjects4,458