There are 130 fully characterized patient cases with high risk Wilms tumor (all tumor/normal pairs; 8 with additional samples for analysis = 3 with tumor adjacent normal, 5 with relapse sample) that will make up the TARGET WT dataset. Each case will have gene expression, tumor and paired normal copy number analyses, methylation and whole genome sequencing; a subset of WT cases with mRNA-seq, miRNA-seq, and whole exome sequencing data available as well. All cases can be sorted according to data type via the Case Matrix on the TARGET Data Matrix. Please visit the TARGET website, http://ocg.cancer.gov/programs/target, for additional information on this and other TARGET genomics projects. Please see the TARGET Publication Guidelines at the OCG website for updated details on sharing of any TARGET substudy data.