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TARGET: Acute Lymphoblastic Leukemia (ALL) Expansion Phase 2

phs000464.v20.p8dbGapdbGap FHIR

Description

There are 175 fully characterized patient cases with relapsed precursor B-cell ALL (all tumor/normal pairs, 85 with relapse sample as well) that will make up Phase II of the TARGET ALL dataset, each with gene expression, tumor and paired normal copy number analyses, and comprehensive next-generation sequencing to include whole genome sequencing, mRNA-seq and miRNA-seq. Subsets of these cases will also have methylation and/or whole exome sequencing data available as well. There are additionally a large number of cases with partial molecular characterization making this a large and informative genomic dataset. All cases can be sorted according to data type via the Case Matrix on the TARGET Data Matrix. Please visit the TARGET website, http://ocg.cancer.gov/programs/target, for additional information on this and other TARGET genomics projects. Please see the TARGET Publication Guidelines at the OCG website for updated details on sharing of any TARGET substudy data.

Summary

PlatformsCRDC
Consent CodesPCR
Focus / DiseasesPrecursor Cell Lymphoblastic Leukemia-Lymphoma
Study DesignTumor vs. Matched-Normal
Data TypesRNA-Seq, WGS, WXS, miRNA-Seq
Subjects1,199