NHLBI TOPMed - NHGRI CCDG: Vanderbilt University BioVU Atrial Fibrillation Genetics Study
Description
Atrial fibrillation (also called AFib or AF) is a quivering or irregular heartbeat (arrhythmia) that can lead to blood clots, stroke, heart failure and other heart-related complications. At least 2.7 million Americans are living with AFib. Individuals with early onset atrial fibrillation (AF) are included in this study of cases from the BioVU sample repository. BioVU is Vanderbilt's biobank of DNA extracted from leftover and otherwise discarded clinical blood specimens. BioVU operates as a consented biorepository; all individuals must sign the BioVU consent form in order to donate future specimens. BioVU subjects are de-identified and linked to the Synthetic Derivative enabling researchers to access genetic data/DNA material as well as dense, longitudinal electronic medical record (EMR) information.
Stats
Summary
Terra Workspaces
This study has been divided into the following workspaces by consent codes and optionally the originating laboratory.
| Terra Workspace Name | Consent Code | Disease | Access | Study Design | Data Type | Samples | Participants | Size (TB) |
|---|---|---|---|---|---|---|---|---|
| AnVIL_CCDG_Baylor_CVD_AFib_BioVU_WGS | Consortia Access Only | atrial fibrillation | Consortium Access Only | Case Set | Whole Genome | 1,122 | 1,122 | 26.79 |
| AnVIL_CCDG_Broad_CVD_AF_BioVU_HMB_GSO_Arrays | NA | inflammatory bowel disease | Consortium Access Only | Case-Control | Genotyping Array | 3 | 3 | 0.00 |
| AnVIL_CCDG_Broad_CVD_AF_BioVU_HMB_GSO_WES | atrial fibrillation | Controlled Access | Case Set | Exome | 5,031 | 5,031 | 4.65 | |
| AnVIL_CCDG_TOPMed_WashU_CVD_Afib_BioVu_WGS | TBD | atrial fibrillation | Controlled Access | TBD | TBD | 988 | 988 | 19.15 |
