Center for Common Disease Genomics [CCDG] - Cardiovascular: The Bangladesh Risk of Acute Vascular Events (BRAVE) Study
Description
The Bangladesh Risk of Acute Vascular Events (BRAVE) study is a hospital-based case-control study in Bangladesh which was established by the Cardiovascular Epidemiology Unit of Cambridge University in the UK in partnership with the key local cardiology and research centres to examine environmental, genetic, lifestyle and biochemical determinants of myocardial infarction (MI) among this South Asian population. By the end of 2016, this study has recruited ~8000 clinically confirmed first-ever MI cases (with a significant proportion being early-onset MI), and ~8000 healthy controls frequency-matched by age and sex. This site hosts data from ~500 whole genomes and ~1500 whole exomes (50% cases and 50% controls)
Stats
Summary
Terra Workspaces
This study has been divided into the following workspaces by consent codes and optionally the originating laboratory.
| Terra Workspace Name | Consent Code | Disease | Access | Study Design | Data Type | Samples | Participants | Size (TB) |
|---|---|---|---|---|---|---|---|---|
| AnVIL_CCDG_Broad_CVD_Stroke_BRAVE_WGS | GRU | myocardial infarction | Controlled Access | Prospective Longitudinal Cohort | Whole Genome | 496 | 496 | 6.34 |
| AnVIL_CCDG_Broad_MI_BRAVE_GRU_WES | GRU | myocardial infarction | Controlled Access | Prospective Longitudinal Cohort | Exome | 1,496 | 1,496 | 2.47 |
