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NHGRI Analysis Visualizationand Informatics Lab-space
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NHLBI TOPMed - NHGRI CCDG: Genes-Environments and Admixture in Latino Asthmatics (GALA II)

CCDGphs000920.v4.p2dbGapdbGap FHIR

Description

This is a case-only pharmacogenetic study of bronchodilator drug response among racially admixed Latino children with asthma. Each participant had two spirometry measurements using the KoKo PFT System. With the first spirometry test, participant was administered with 4 puffs of HFA Albuterol. The second albuterol measurement was based on age, for participants under 16 years of age, additional 2 puffs were administered and for those over 16 years of age, additional 4 puffs were administered. The overall goal is to identify genetic factors which are predictive of drug response in children with asthma. The principal tools include a questionnaire and biological specimen collection. Participants are 8-21 years old at time of recruitment. Children with asthma have physician-diagnosed asthma, symptoms and medications.

Comprehensive phenotypic data for GALAII study participants are available through dbGaP phs001180.

Stats

1Cohorts
1,171Samples
1,171Participants
28.70 TBSize

Summary

Consent CodesDS-LD-RD
Diseasesasthma
AccessControlled Access
Study DesignCase Set
Data TypesWhole Genome

Terra Workspaces

This study has been divided into the following workspaces by consent codes and optionally the originating laboratory.

Terra Workspace NameConsent CodeDiseaseAccessStudy DesignData TypeSamplesParticipantsSize (TB)
AnVIL_CCDG_NYGC_AI_Asthma_Gala2_WGSDS-LD-RDasthmaCase SetWhole Genome1,1711,17128.70